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cannabis COVID19

Cannabidiol (CBD) inhibit SARS-CoV-2 replication and promotes the host innate immune response

Scientists from University of Chicago, US published a research paper showing cannabis extract, namely cannabidiol, inhibited severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to replicate. Furthermore, scientists showed that cannabidiol effectively reversed the viral induction of cytokines that can trigger a deadly hyperinflammatory response called the cytokine storm during the later stages of infection. Establishment […]

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cannabis

Science shows cannabidiol is a natural sunscreen to block UVA or UVB radiation

UV radiation is a well-established environmental risk factor known to cause oxidative stress and disrupt the metabolism of keratinocyte phospholipids so many people are using sunscreen. Scientists tried to see if cannabidiol (CBD) could be used as a natural sunscreen. CBD is a phytocannabinoid with anti-inflammatory and antioxidant effects. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761402/ When CBD was applied on […]

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cannabis

The potential of cannabidiol in the COVID‐19 pandemic

A group of authors from Italy, Spain and China suggest that Cannabidiol (CBD) has the potential to limit the severity and progression of the disease for several reasons: CBD:(a) down-regulates the expression of the two key receptors for SARS-CoV2 in several models of human epithelia,(b) mitigates cytokine production for acute lung injury(c) displays a direct […]

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cannabis

Biological effects of Cannabidiol on normal human healthy cell populations: Systematic review of the literature

Highlights •CBD shows biological effects on human cells in a dose- and time-dependent manner. •CBD appears to exhibit effects with dosages above 10 μM on oral cell populations. •Cell viability, proliferation and migration are inhibited with high doses of CBD. •The anti-inflammatory effect results homogeneous in terms of mediator production. The down-regulation of inflammatory mediators […]

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cannabis COVID19

CBD can reduce the cytokine storm and treat ARDS caused by COVID-19

Scientists showed a potential protective role for CBD during Acute Respiratory Distress Syndrome(ARDS), and suggested CBD could be the treatment of COVID-19 by reducing the cytokine storm, protecting pulmonary tissues, and re-establishing inflammatory homeostasis. Acute Respiratory Distress Syndrome (ARDS) is a life-threatening complication that makes patient unable to breathe as their lung become filled with […]

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cannabis COVID19

Cannabidiol helped allergic asthma by reducing airway inflammation and fibrosis

Asthma remains a major public health problem and, at present, there are no effective interventions capable of reversing airway remodelling. Asthma is characterized by chronic lung inflammation and airway hyperresponsiveness. Vuolo F, Abreu SC, Michels M, Xisto DG, Blanco NG, Hallak JE, Zuardi AW, Crippa JA, Reis C, Bahl M, Pizzichinni E, Maurici R, Pizzichinni […]